Probiotic property and anti-obesity effect of Lactiplantibacillus plantarum KC3

Seulki Kim¹, Eunchong Huang², Yosep Ji², Wilhelm Helnrich Holzapfel², Sang-Dong Lim¹^,^*

Author Information & Copyright ▼

¹Korea Food Research Institute, Wanju 55365, Korea.

²Advanced Green Energy and Environment, Handong Global University, Pohang 37673, Korea.

^*Corresponding Author: Sang-Dong Lim, Korea Food Research Institute, Wanju 55365, Korea. E-mail: limsd@kfri.re.kr.

© Copyright 2022 Korean Society for Food Science of Animal Resources. This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Received: Jun 21, 2022 ; Revised: Jul 22, 2022 ; Accepted: Aug 11, 2022

Published Online: Aug 11, 2022

Abstract

Lactic acid bacteria (LAB) are representative probiotics that have beneficial effects on humans. Nineteen strains among the 167 single strains from kimchi was selected and investigated their physiological features. The selection of a strain was based on strong enzyme (lipase, α-amylase and α-glucosidase) inhibitory activities and anti-obesity effects in the adipocytes. For the final selection, the strain Lactiplantibacillus plantarum KC3 was tested for its potential as a starter. To assess its functionality, a freeze-dried culture of L. plantarum KC3 was administered to a diet-induced obese mouse model receiving a high-fat diet. The animal group administered with L. plantarum KC3 showed significant body weight loss during the 12-week feeding period compared to the high-fat control group. This study investigated the physiological characteristics of selected strain and evaluated its potential as an anti-obesity probiotic in mice.

Keywords: lactic acid bacteria; L. plantarum; probiotics; anti-obesity; probiotic property