Probiotic property and anti-obesity effect of Lactiplantibacillus plantarum KC3
Received: Jun 21, 2022 ; Revised: Jul 22, 2022 ; Accepted: Aug 11, 2022
Published Online: Aug 11, 2022
Lactic acid bacteria (LAB) are representative probiotics that have beneficial effects on humans. Nineteen strains among the 167 single strains from kimchi was selected and investigated their physiological features. The selection of a strain was based on strong enzyme (lipase, α-amylase and α-glucosidase) inhibitory activities and anti-obesity effects in the adipocytes. For the final selection, the strain Lactiplantibacillus plantarum KC3 was tested for its potential as a starter. To assess its functionality, a freeze-dried culture of L. plantarum KC3 was administered to a diet-induced obese mouse model receiving a high-fat diet. The animal group administered with L. plantarum KC3 showed significant body weight loss during the 12-week feeding period compared to the high-fat control group. This study investigated the physiological characteristics of selected strain and evaluated its potential as an anti-obesity probiotic in mice.