Use of Postbiotic as Growth Promoter in Poultry Industry- Current Knowledge and Future Prospects

Muhammad Saeed1,,*, Zoya Afzal2,, Fatima Afzal3, Rifat Ullah Kha4, Shaaban S. Elnesr5, Mahmoud Alagawany6, Huayou Chen1
Author Information & Copyright
1School of Life Sciences, Jiangsu University, Zhenjiang, 212013, China, Jiangsu 212013, China.
2Department of Poultry Science, Faculty of Animal Production and Technology, The Cholistan University of Veterinary and Animal Sciences, Bahawalpur, Pakistan, Bahawalnagar 62300, Pakistan.
3Department of Life Sciences, Sogang University, South Korea, Seoul 04107, Korea.
4College of Veterinary Sciences, Faculty of Animal Husbandry and Veterinary Sciences, The University of Agriculture Peshawar, Peshawar, Pakistan, Peshawar 25120, Pakistan.
5Department of Poultry Production, Faculty of Agriculture, Fayoum University, 63514 Fayoum, Egypt , Fayoum 63514, Egypt.
6Department of Poultry, Faculty of Agriculture, Zagazig University, Zagazig 44511, Egypt, Zagazig 44511, Egypt.

† These authors contributed equally to this work.

*Corresponding Author: Muhammad Saeed. E-mail:

© Copyright 2023 Korean Society for Food Science of Animal Resources. This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Received: May 06, 2023 ; Revised: Aug 23, 2023 ; Accepted: Sep 07, 2023

Published Online: Sep 08, 2023


Health-promoting preparations of inanimate microorganisms or their components are postbiotics. Since probiotics are sensitive to heat and oxygen, postbiotics are stable during industrial processing and storage. Postbiotics boost poultry growth, feed efficiency, intestinal pathogen reduction, and health, making them acceptable drivers of sustainable poultry production. It contains many important biological properties, such as immunomodulatory, antioxidant, and anti-inflammatory responses. Postbiotics revealed promising antioxidant effects due to higher concentrations of uronic acid and due to some enzyme's production of antioxidants, e.g., superoxide dismutase, glutathione peroxidase, and nicotinamide adenine dinucleotide oxidases and peroxidases. Postbiotics improve intestinal villi, increase lactic acid production, and reduce Enterobacteriaceae and fecal pH, all of which lead to a better immune reaction and health of the gut, as well as better growth performance. P13K/AKT as a potential target pathway for postbiotics-improved intestinal barrier functions. Similarly, postbiotics reduce yolk and plasma cholesterol levels in layers and improve egg quality. It was revealed that favorable outcomes were obtained with various inclusion levels at 1 kg and 0.5 kg. According to several studies, postbiotic compounds significantly increased poultry performance. This review article presents the most recent research investigating the beneficial results of postbiotics in poultry.

Keywords: Postbiotic; antibiotic alternatives; mechanism of action; Poultry