Short Communication

Effect of flutriafol exposure on residue characteristics in pig muscle and fat tissue

Jin Young Jeong1,*, Byeonghyeon Kim1, Sang Yun Ji1, Youl Chang Baek1, Minji kim1, Seol Hwa Park1, Hyunjung Jung1
Author Information & Copyright
1Animal Nutrition & Physiology Division, National Institute of Animal Science, Wanju 55365, Korea.
*Corresponding Author: Jin Young Jeong, Animal Nutrition & Physiology Division, National Institute of Animal Science, Wanju 55365, Korea. E-mail: jeong73@korea.kr.

© Copyright 2021 Korean Society for Food Science of Animal Resources. This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Received: Sep 17, 2021 ; Revised: Oct 13, 2021 ; Accepted: Oct 14, 2021

Published Online: Nov 08, 2021

Abstract

This study investigated the effect of exposure to flutriafol based on residues in pigs. Pigs were exposed to different concentrations (0.313, 0.625, 3.125, 6.25, and 12.5 mg/kg bw/d, n = 20) for 4 wks in different treatment groups. Serum biochemical analysis, residue levels, and histological analysis were conducted using the VetTest chemistry analyzer, liquid chromatography mass spectrometry, and Masson's trichrome staining, respectively. The body weight (initialand final) was not significantly different between groups. Parameters such as creatinine, blood urea nitrogen, alanine aminotransferase, and lipase levels were significantly different as compared to the control group. Flutriafol increased the residue limits in individual tissue of the pigs in a dose dependent manner. Flutriafol exposures indicated the presence of fibrosis, as confirmed from Masson's trichrome staining. These results suggest that flutriafol affects the morphology and serum levels in pigs. The dietary flutriafol levels can provide a basis for maximum residue limits and food safety for pig meat and related products.

Keywords: pig; flutriafol; fibrosis


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Special Issue: 67th ICoMST 2021


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