Table 3. Association between FASN gene polymorphism and fatty acid composition
Fatty acid | FASN genotype | p-value |
AA | AG | GG |
SFA |
C4:0 | 3.2351±0.025 | 3.2915±0.019 | 3.2415±0.022 | 0.220 |
C6:0 | 2.3977±0.047 | 2.3311±0.036 | 2.4345±0.040 | 0.208 |
C8:0 | 1.0073±0.013 | 1.0263±0.010 | 1.0272±0.011 | 0.457 |
C10:0 | 2.15315±0.0099 | 2.13910±0.0075 | 2.14489±0.0084 | 0.606 |
C11:0 | 0.32278±0.0095 | 0.34847±0.0072 | 0.33532±0.0081 | 0.177 |
C12:0 | 3.2837±0.069 | 3.2842±0.052 | 3.2192±0.058 | 0.632 |
C13:0 | 0.1737±0.019 | 0.1801±0.014 | 0.1893±0.016 | 0.780 |
C14:0 | 14.034±0.15b | 13.762±0.11a | 14.022±0.12a | 0.022* |
MUFA |
C14:1 | 1.2274±0.012 | 1.21490±0.0091 | 1.2263±0.010 | 0.693 |
C18:1 trans6 | 0.36629±0.0073 | 0.37404±0.0055 | 0.36428±0.0062 | 0.541 |
C18:1 trans9 | 0.22849±0.0079ab | 0.21516±0.0060a | 0.22188±0.0067b | 0.028* |
C18:1 trans10 | 0.36345±0.0097 | 0.35605±0.0074 | 0.36088±0.0083 | 0.860 |
C18:1 trans11 | 1.4424±0.015b | 1.4729±0.011a | 1.4737±0.012a | 0.030* |
C18:1 cis9 | 19.175±0.20 | 19.545±0.15 | 19.444±0.17 | 0.398 |
C24:1 n9 | 1.1290±0.047a | 1.2564±0.036ab | 1.2450±0.040a | 0.002* |
PUFA |
C18:2n6 | 0.4475±0.027a | 0.4343±0.020b | 0.4169±0.023a | 0.034 |
C18:3n6 | 3.4448±0.032 | 3.4094±0.024 | 3.4132±0.027 | 0.673 |
C18:3n3 | 0.4653±0.017a | 0.4575±0.013b | 0.4187±0.015ab | 0.013 |
C20:2 | 0.13425±0.0065 | 0.14402±0.0050 | 0.13840±0.0056 | 0.576 |
C20:5n3 | 0.38624±0.0073 | 0.40196±0.0056 | 0.38854±0.0062 | 0.249 |
C22:6 n3 | 0.21220±0.0093a | 0.18202±0.0071a | 0.19776±0.0080b | 0.004* |
Different superscript letters within the same row mean significantly different between genotype (p<0.05).
p<0.05.
FASN, fatty acid synthase; AA, 273, 217, 167, and 101 bp; AG, 440, 273, 217, 167, and 101 bp; GG, 440, 217, and 101 bp; SFA, saturated fatty acid; MUFA, monounsaturated fatty acid; PUFA, polyunsaturated fatty acid.