Table 2. The concentration of short-chain fatty acids (SCFAs) in SD rats with loperamide-induced constipation
Groups1) | The concentration of short-chain fatty acids (SCFAs, ppm) |
Acetic acid | Propionic acid | Butyric acid | Total SCFAs |
G1 | 965.90±117.38 | 1,646.50±488.85 | 77.66±49.61 | 2,690.05±532.05 |
G2 | 673.93±191.19† | 913.80±816.80 | 50.45±87.37 | 1,638.18±645.56† |
G3 | 836.04±345.12 | 1,698.273±960.82 | 15.06±30.11 | 2,549.37±1,271.69 |
G4 | 1,219.60±203.51* | 2,426.44±721.84 | 27.64±47.87 | 3,673.67±568.99* |
G5 | 1,207.09±318.78 | 1,940.17±1,549.11 | 62.03±124.06 | 3,209.29±1,371.95 |
G6 | 1,292.25±209.91* | 2,601.30±921.44 | <5 | 3,893.55±1,031.94* |
Values are means±standard deviation (n=10).
G1, normal group; G2, loperamide-induced constipation group; G3, Bacillus subtilis IDCC 1101 and loperamide-induced constipation group; G4, Weizmannia coagulans IDCC 1201 and loperamide-induced constipation group; G5, Clostridium butyricum IDCC 1301 and loperamide-induced constipation group; G6, BIOVITA 3 and loperamide-induced constipation group.
p<0.05 vs. G1
p<0.05 vs. G2.
SD, Sprague-Dawley.