Table 2. DEGs between WIKIM28-treated macrophages and WIKIM50-treated macrophages1)

Gene symbol Gene description Fold increase Accession number
Up-regulated genes in WIKIM50-treated macrophages compared to those in WIKIM28
cd55 CD55 antigen 4.04 NM_010016
card11 Caspase recruitment domain family, member 11 3.97 NM_175362
rgs2 Regulator of G-protein signaling 2 3.64 NM_009061
cxcr3 Chemokine (C-X-C motif) receptor 3 3.35 NM_009910
mafb v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) 2.99 NM_010658
tlr12 Toll-like receptor 12 2.79 NM_205823
nlrp1b NLR family, pyrin domain containing 1B 2.78 NM_001040696
mrc1 Mannose receptor, C type 1 2.74 NM_008625
nfatc2 Nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 2.63 NM_001136073
cd93 CD93 antigen 2.62 NM_010740
il6ra Interleukin 6 receptor, alpha 2.51 NM_010559
thbs1 Thrombospondin 1 2.47 NM_011580
st6gal1 Beta galactoside alpha 2,6 sialyltransferase 1 2.45 NM_145933
pparg Peroxisome proliferator activated receptor gamma 2.36 NM_011146
ccl6 Chemokine (C-C motif) ligand 6 2.34 NM_009139
c3ar1 Complement component 3a receptor 1 2.33 NM_009779
sepp1 Selenoprotein P, plasma, 1 2.22 NM_001042614
anxa1 Annexin A1 2.12 NM_010730
ccr5 Chemokine (C-C motif) receptor 5 2.12 NM_009917
masp1 Mannan-binding lectin serine peptidase 1 2.07 XM_006521828
iqgap3 IQ motif containing GTPase activating protein 3 2.04 NM_001033484
cd300lb CD300 antigen like family member B 2.02 NM_199221
alox5 Arachidonate 5-lipoxygenase 2.01 NM_009662
celf2 CUGBP, Elav-like family member 2 2.01 NM_010160
clec9a C-type lectin domain family 9, member a 2.00 NM_001205363
Down-regulated genes in WIKIM50-treated macrophages compared to those in WIKIM28
cxcl2 Chemokine (C-X-C motif) ligand 2 –22.80 NM_009140
cxcl1 Chemokine (C-X-C motif) ligand 1 –17.74 NM_008176
ptgs2 Prostaglandin-endoperoxide synthase 2 –11.32 NM_011198
cav1 Caveolin 1, caveolae protein –9.92 NM_001243064
cxcl5 Chemokine (C-X-C motif) ligand 5 –5.33 NM_009141
tnf Tumor necrosis factor –5.25 NM_013693
il1a Interleukin 1 alpha –4.74 NM_010554
hdac9 Histone deacetylase 9 –4.64 NM_024124
dnmt3l DNA (cytosine-5-)-methyltransferase 3-like –4.51 NM_019448
nlrp1a NLR family, pyrin domain containing 1A –3.35 NM_001004142
maff v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian) –3.30 NM_010755
cxcl10 Chemokine (C-X-C motif) ligand 10 –3.23 NM_021274
il20rb Interleukin 20 receptor beta –3.21 NM_001033543
ccl3 Chemokine (C-C motif) ligand 3 –3.10 NM_011337
cd40 CD40 antigen –3.00 NM_011611
ccl7 Chemokine (C-C motif) ligand 7 –2.96 NM_013654
il10 Interleukin 10 –2.94 NM_010548
socs1 Suppressor of cytokine signaling 1 –2.80 NM_009896
socs3 Suppressor of cytokine signaling 3 –2.72 NM_007707
rgs16 Regulator of G-protein signaling 16 –2.57 NM_011267
cd38 CD38 antigen –2.40 NM_007646
DEGs with at least 2 folds.
DEGs, differentially expressed genes.