Table 1. Urinalysis data of Sprague-Dawley (SD) rats orally administered fdLM for 28 days
Parameters | Result | fdLM (mg/kg/day) |
0 | 750 | 1,500 | 3,000 |
Male |
GLU | − | 5 | 5 | 5 | 5 |
BIL | − | 5 | 5 | 5 | 5 |
KET | − | 4 | 4 | 5 | 3 |
| +/− | 1 | 1 | 0 | 2 |
pH | 7.5 | 1 | 2 | 0 | 1 |
| 8.0 | 2 | 1 | 2 | 2 |
| 8.5 | 2 | 2 | 3 | 2 |
PRO | − | 5 | 5 | 5 | 5 |
URO | 0.2 | 5 | 5 | 5 | 5 |
NIT | − | 5 | 5 | 4 | 4 |
| + | 0 | 0 | 1 | 1 |
BLO | − | 5 | 5 | 5 | 5 |
Female |
GLU | − | 5 | 5 | 5 | 5 |
BIL | − | 5 | 5 | 5 | 5 |
KET | − | 5 | 5 | 5 | 5 |
pH | 7.5 | 0 | 0 | 1 | 1 |
| 8.0 | 1 | 1 | 3 | 1 |
| 8.5 | 4 | 4 | 1 | 2 |
| 9.0 | 0 | 0 | 0 | 1 |
PRO | − | 5 | 5 | 5 | 5 |
URO | 0.2 | 5 | 5 | 5 | 5 |
NIT | − | 2 | 4 | 2 | 2 |
| + | 3 | 1 | 3 | 3 |
BLO | − | 5 | 5 | 5 | 5 |
Significant difference at p<0.05 levels compared to the vehicle control (n=5).
fdLM, freeze-dried powder of Locusta migratoria; GLU, glucose; BIL, bilirubin; KET, ketone body; PRO, protein; URO, urobilinogen; NIT, nitrite; BLO, occult blood; NA, not applicable.