Table 3 MIC values of antibiotics for Clostridium difficile isolates by E-test
Antibiotics | MIC breakpoints (µg/mL) | MIC values of C. difficile isolates (µg/mL) |
S | I | R | MB025 | ED046 |
Metronidazole1) | >8 | 16 | >256 | 0.125 | >256 |
Moxifloxacin1) | >2 | 4 | >8 | 0.75 | 0.38 |
Tetracycline1) | >4 | 8 | >16 | 48 | 0.047 |
Clindamycin1) | >2 | 4 | >8 | 0.6 | 0.19 |
Vancomycin2) | >2 | - | >2 | >256 | 4 |
1) The breakpoints defined by Clinical and Laboratory Standards Institute (CLSI).
2) The breakpoints defined by European Committee for Antimicrobial Susceptibility Testing (EUCAST).
MIC, minimum inhibition concentration; S, susceptible; I, intermediate; R, resistant.