Table 4. Serum biochemical parameters of Sprague-Dawley (SD) rats orally administered TMlp for 5 weeks
Parameters | Control | TMlp |
W/o eps 10% | W/ eps 5% | W/ eps 10% | W/ eps 15% |
TP (g/dL) | 5.74±0.26 | 5.78±0.19 | 5.90±0.21 | 5.95±0.21 | 5.93±0.17 |
Albumin (g/dL) | 3.56±0.15 | 3.64±0.14 | 3.67±0.10 | 3.77±0.11 | 3.70±0.06 |
T-Bili (mg/dL) | LOD1) | 0.0043±0.0086 | LOD | LOD | 0.0167±0.0373 |
Glucose (mg/dL) | 224.80±7.17 | 222.40±19.44 | 212.80±16.12 | 204.50±17.64 | 212.83±19.92 |
BUN (mg/dL) | 15.84±0.51 | 15.04±2.37 | 15.38±1.23 | 14.95±1.89 | 13.85±1.85 |
Crea (mg/dL) | 0.26±0.05 | 0.26±0.05 | 0.26±0.05 | 0.27±0.05 | 0.25±0.05 |
AST (U/L) | 123.20±32.76 | 95.20±27.95 | 104.60±22.22 | 95.17±20.91 | 80.50±6.24 |
ALT (U/L) | 61.93±5.11 | 57.98±5.87 | 56.17±2.27 | 59.61±2.92 | 56.47±5.19 |
ALP (U/L) | 332.80±56.60 | 334.40±31.93 | 294.60±46.77 | 308.83±13.86 | 299.00±39.49 |
γ-GTP (U/L) | 0.96±0.33 | 1.05±0.32 | 1.04±0.36 | 0.97±0.23 | 0.77±0.17 |
Globulin (g/dL) | 2.18±0.12 | 2.14±0.08 | 2.22±0.12 | 2.18±0.13 | 2.23±0.18 |
Na+ (mmol/L) | 138.32±0.52 | 139.20±0.51* | 139.98±1.32 | 139.98±0.53# | 140.00±0.49 |
K+ (mmol/L) | 4.41±0.30 | 4.00±0.31 | 4.09±0.34 | 4.45±0.57 | 4.23±0.30 |
Cl– (mmol/L) | 98.20±0.35 | 99.02±0.63 | 99.04±1.16 | 99.15±1.13 | 98.70±1.03 |
Values are presented as mean±SD (n=5).
Significance was determined using Student’s t-test.
p<0.05 compared with control versus W/o eps 10%.
p<0.05 compared with W/o eps 10% versus W/ eps 10%.
LOD, below the limit of detection.
TMlp, Tenebrio molitor larvae powder; W/o eps, without expanded-polystyrene-fed; W/ eps, expanded-polystyrene-fed; TP, total protein; T-Bili, total bilirubin; BUN, blood urea nitrogen; Crea, creatinine; AST, aspartate aminotransferase; ALT, alanine aminotransferase; ALP, alkaline phosphatase; γ-GTP, gamma glutamyl transpeptidase.